Human FAM3B Isoform B Antibody

R&D Systems, part of Bio-Techne | Catalog # AF2866

R&D Systems, part of Bio-Techne
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AF2866
AF2866-SP
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

View all FAM3B Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FAM3B isoform B
Glu30-Ser235
Accession # P58499

Specificity

Detects human FAM3B in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 35% cross‑reactivity with recombinant mouse FAM3B is observed and less than 5% cross-reactivity with recombinant human FAM3C is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human FAM3B Isoform B Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human FAM3B Isoform B

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FAM3B

FAM3B, also known as Pancreatic-derived factor (PANDER), is a secreted 23 kDa glycoprotein that belongs to the cytokine like-protein family. Members of this family share a four-helix bundle secondary structure similar to that found in many cytokines. As a result of alternative splicing and alternate signal peptide cleavage sites, multiple isoforms are known. FAM3B is expressed by pancreatic islet alpha and beta-cells, reproductive epithelium and a subset of neurons. Recombinant FAM3B has been shown to induce beta-cell apoptosis. The amino acid sequence of mature human FAM3B is 80% identical to that of mature mouse FAM3B.

Long Name

Family With Sequence Similarity 3, Member B

Alternate Names

PANDER, PRED44

Entrez Gene IDs

54097 (Human)

Gene Symbol

FAM3B

UniProt

P58499 (Human)

Additional FAM3B Products

Product Documents for Human FAM3B Isoform B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human FAM3B Isoform B Antibody

For research use only

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