Human FCRL4/FcRH4 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB24262
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
CyTOF-ready, Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 580810
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4
Gln16-Asp385
Accession # NP_112572
Gln16-Asp385
Accession # NP_112572
Specificity
Detects human FCRL4/FcRH4 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human FCRL1 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Human FCRL4/FcRH4 Antibody
Detection of FCRL4/FcRH4 in RPMI 8226 Human Cell Line by Flow Cytometry.
RPMI 8226 human multiple myeloma cell line was stained with Mouse Anti-Human FCRL4/FcRH4 Monoclonal Antibody (Catalog # MAB24262, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).Applications for Human FCRL4/FcRH4 Antibody
Application
Recommended Usage
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
Flow Cytometry
2.5 µg/106 cells
Sample: RPMI 8226 human multiple myeloma cell line
Sample: RPMI 8226 human multiple myeloma cell line
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: FCRL4/FcRH4
Fc receptor-like 4 (FCRL4), also known as FcRH4 and IRTA1, is an Ig superfamily transmembrane protein that shares sequence homology with the classical Fc receptors. FCRL4 is preferentially expressed in B cells and contains three potential ITIM motifs in its cytoplasmic domain. The gene for FCRL4 is localized to the human chromosome 1q21‑23 region, a hotspot for translocation events.
Long Name
Fc Receptor-like protein 4
Alternate Names
CD307d, FcRH4, IGFP2, IRTA1
Entrez Gene IDs
83417 (Human)
Gene Symbol
FCRL4
UniProt
Additional FCRL4/FcRH4 Products
Product Documents for Human FCRL4/FcRH4 Antibody
Product Specific Notices for Human FCRL4/FcRH4 Antibody
For research use only
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