Human FGFR1 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB658

R&D Systems, part of Bio-Techne
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MAB658-100
MAB658-500
MAB658-SP
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 133105

View all FGFR1 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FGF R1 alpha (IIIc)

Specificity

Detects human FGF R1 in direct ELISAs and Western blots. Recognizes all isoforms of recombinant human (rh) FGF R1 and shows10-25% cross-reactivity with various isoforms of rhFGF R2 and rhFGF R3.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human FGFR1 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human FGF R1 alpha (IIIb) Fc Chimera (Catalog # 655-FR)
Recombinant Human FGF R1 alpha (IIIc) Fc Chimera (Catalog # 658-FR)
Recombinant Human FGF R1 beta (IIIb) Fc Chimera (Catalog # 765-FR)
Recombinant Human FGF R1 beta (IIIc) Fc Chimera (Catalog # 661-FR)

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FGFR1

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

Long Name

Fibroblast Growth Factor Receptor 1

Alternate Names

CD331, FGF R1, Flt-2

Entrez Gene IDs

2260 (Human); 14182 (Mouse)

Gene Symbol

FGFR1

Additional FGFR1 Products

Product Documents for Human FGFR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human FGFR1 Antibody

For research use only

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