Human GR/NR3C1 Antibody (Clone H8031)
R&D Systems, part of Bio-Techne | Catalog # PP-H8031-00
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # H8031
Product Summary for Human GR/NR3C1 Antibody (Clone H8031)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for Human GR/NR3C1 Antibody (Clone H8031)
Application
Recommended Usage
Immunohistochemistry
5-15 µg/mL
Sample: Perfusion fixed paraffin-embedded sections of rat pancreas
Sample: Perfusion fixed paraffin-embedded sections of rat pancreas
Immunoprecipitation
Western Blot
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Reviewed Applications
Read 1 review rated 5 using PP-H8031-00 in the following applications:
Formulation, Preparation, and Storage
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: GR/NR3C1
Glucocorticoid receptor (GR; NR3C1) is a member of the steroid receptor family. GR are expressed in almost all human tissues and organs. GR bind to its sequences as a homodimer. Two different forms, GR-alpha and GR-beta, differing in their C-terminal parts were isolated. GR-alpha is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GR-beta does not bind glucocorticoids.
Long Name
Glucocorticoid Receptor
Alternate Names
NR3C1
Entrez Gene IDs
2908 (Human)
Gene Symbol
NR3C1
Additional GR/NR3C1 Products
Product Documents for Human GR/NR3C1 Antibody (Clone H8031)
Product Specific Notices for Human GR/NR3C1 Antibody (Clone H8031)
For research use only
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