Human Histamine H1 R PE-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB4726P
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 480054
Product Specifications
Immunogen
NS0 mouse myeloma cell line transfected with human Histamine H1 R
Met1-Ser487
Accession # AAH60802
Met1-Ser487
Accession # AAH60802
Specificity
Detects human Histamine H1 R. Stains human Histamine H1 R transfectants but not irrelevant transfectants.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Human Histamine H1 R PE-conjugated Antibody
Detection of Histamine H1 R in U937 human histiocytic lymphoma cell line activated with PMA by Flow Cytometry.
U937 human histiocytic lymphoma cell line, resting (A) or (B) activated with PMA, was stained with Mouse Anti-Human Histamine H1 R PE-conjugated Monoclonal Antibody (Catalog # FAB4726P, filled histograms) or isotype control antibody (Catalog # IC002P, open histograms). View our protocol for Staining Membrane-associated Proteins.Applications for Human Histamine H1 R PE-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: U937 human histiocytic lymphoma cell line activated with PMA
Sample: U937 human histiocytic lymphoma cell line activated with PMA
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: Histamine H1 R
Histamine H1 R (HRH1) is a 60 kDa, 487 aa G-protein coupled 7-transmembrane putative glycoprotein. It is implicated in the pathogenesis of asthma and is a major pharmaceutical target for antihistamines. It has been detected as a mixture of monomers and homodimers, with highest concentration in the placenta, followed by brain, lung (produced by airway smooth muscle, bronchial epithelium and macrophages) and other tissues. Extracellular domains of human HRH1 share 72% aa sequence identity with corresponding regions of mouse or rat HRH1.
Long Name
Histamine H1 Receptor
Alternate Names
H1-R, Histamine H1R, HRH1
Gene Symbol
HRH1
UniProt
Additional Histamine H1 R Products
Product Documents for Human Histamine H1 R PE-conjugated Antibody
Product Specific Notices for Human Histamine H1 R PE-conjugated Antibody
For research use only
Loading...
Loading...
Loading...
Loading...
Loading...