Detects human ILT1/CD85h in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Scientific Data Images for Human ILT1/CD85h APC-conjugated Antibody

Detection of ILT1/CD85h in Human Blood Monocytes by Flow Cytometry.

Human peripheral blood monocytes were stained with Mouse Anti-Human ILT1/CD85h APC-conjugated Monoclonal Antibody (Catalog # FAB6364A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human ILT1/CD85h APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Human peripheral blood monocytes

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: LILRA2/CD85h/ILT1

Immune-Like Transcript 1 (ILT1), also known as Leukocyte Immunoglobulin-like Receptor 7 (LIR-7), Leukocyte Immunoglobulin-like Receptor subfamily A member 2 (LILRA2), and CD85h, is a 51 kDa (unglycosylated) type I transmembrane glycoprotein and member of the leukocyte immunoglobulin-like receptor family. Human ILT1 is synthesized as a 483 amino acid (aa) precursor that contains a 23 aa signal sequence, a 426 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 13 aa cytoplasmic region. The ECD contains four Ig-like C2-type domains and seven potential sites for N-linked glycosylation. A splice variant produces a second isoform that has a one aa substitution for aa 419-436 in the longer form. There are no murine orthologs for human ILT1. ILT1 may act as a receptor for class I MHC antigens.

Long Name

Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 2

Alternate Names

CD85h, ILT1, LIR7

Entrez Gene IDs

11027 (Human)

Gene Symbol

LILRA2

UniProt

Q8N149 (Human)

Additional LILRA2/CD85h/ILT1 Products

Product Documents for Human ILT1/CD85h APC-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human ILT1/CD85h APC-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human ILT1/CD85h APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6364A

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all LILRA2/CD85h/ILT1 Antibodies »

Product Specifications

Immunogen

Specificity