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Human Integrin  alpha4 beta7/LPAM-1 (Research Grade Vedolizumab Biosimilar) PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB10078P

Recombinant Monoclonal Antibody For Research Use Only
R&D Systems, part of Bio-Techne
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FAB10078P-100

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Hu117

Product Specifications

Immunogen

Human Integrin alpha4 beta7/LPAM‑1

Specificity

Detects human Integrin alpha4 beta7/LPAM‑1 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Vedolizumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images

Detection of Integrin alpha 4 beta 7/LPAM-1 antibody in Human PBMC antibody by Flow Cytometry.

Detection of Integrin alpha 4 beta 7/LPAM-1 in Human PBMC by Flow Cytometry.

Human PBMC were stained with (A) Human Anti-Human Integrin alpha 4 beta 7/LPAM-1 (Research Grade Vedolizumab Biosimilar) PE-conjugated Monoclonal Antibody (Catalog # FAB10078P) or (B) no primary antibody, followed by Mouse anti-Human CD3 APC-conjugated Monoclonal Antibody (Catalog # FAB100A). View our protocol for Staining Membrane-associated Proteins.

Applications

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human PBMC
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: Integrin alpha 4 beta 7/LPAM-1

Vedolizumab is a biosimilar that binds and blocks binds to integrin alpha4 beta7. This product can be used in flow cytometry or various assay formats to block or measure integrin alpha4 beta7.

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Entrez Gene IDs

3676 (Human); 16402 (Mouse)

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices

For research use only

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