Human LILRA1/CD85i/LIR-6 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB3085

R&D Systems, part of Bio-Techne
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MAB3085
MAB3085-SP
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 356316

View all LILRA1/CD85i/LIR-6 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human LILRA1/CD85i/LIR-6
Pro17-Asn461
Accession # O75019

Specificity

Detects human LILRA1/CD85i/LIR-6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) ILT2, rhILT4, rhILT5, rhLIR-4, rhLIR-5, or rhLIR-8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human LILRA1/CD85i/LIR-6 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human LILRA1/CD85i/LIR-6
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: LILRA1/CD85i/LIR-6

Leukocyte Immunoglobulin-like Receptor 6 (LIR-6), also called LILRA1 or CD85i, is a glycoprotein member of the LIR family of leukocyte Ig-like receptors. As an activating LIR, LIR-6 has a short cytoplasmic tail and a charged aa within the TM domain which interacts with FcR gamma. Both four (LIR-6a) and two (LIR-6b) Ig-like domain forms are expressed by monocytes and B cells. Human LIR-6 has no non-primate ortholog, but shows up to 80% aa identity with human ILT-1c and KIR-p91/PIR-B. A mouse homolog, gp49B2, has structural similarity but limited sequence identity.

Long Name

Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 1

Alternate Names

CD85i, LIR-6, LIR6

Entrez Gene IDs

11024 (Human)

Gene Symbol

LILRA1

UniProt

O75019

Additional LILRA1/CD85i/LIR-6 Products

Product Documents for Human LILRA1/CD85i/LIR-6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human LILRA1/CD85i/LIR-6 Antibody

For research use only

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