Human LILRB4/CD85k/ILT3 APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB24251A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 293623
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human ILT3/CD85k
Pro17-His257
Accession # ABM86208
Pro17-His257
Accession # ABM86208
Specificity
Detects human ILT3/CD85k in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with with recombinant human (rh) ILT5 is observed. No cross-reactivity with rhILT1, rhILT2, rhILT4, rhILT7, rhILT11, rhLIR-6 or rhLIR-8 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human LILRB4/CD85k/ILT3 APC-conjugated Antibody
Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry.
Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 Ra/CD123 PE-conjugated Monoclonal Antibody (Catalog # FAB301P) and either (A) Mouse Anti-Human LILRB4/CD85k/ILT3 APC-conjugated Monoclonal Antibody (Catalog # FAB24251A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.Applications for Human LILRB4/CD85k/ILT3 APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood mononuclear cells (PBMCs)
Sample: Human peripheral blood mononuclear cells (PBMCs)
Reviewed Applications
Read 1 review rated 4 using FAB24251A in the following applications:
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: LILRB4/CD85k/ILT3
Immunoglobulin-Like Transcript 3 (ILT3), also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that functions as a receptor for class I MHC antigens. It contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses.
Long Name
Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 4
Alternate Names
CD85k, HM18, ILT3, LIR5
Gene Symbol
LILRB4
UniProt
Additional LILRB4/CD85k/ILT3 Products
Product Documents for Human LILRB4/CD85k/ILT3 APC-conjugated Antibody
Product Specific Notices for Human LILRB4/CD85k/ILT3 APC-conjugated Antibody
For research use only
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