Human/Mouse BMPR-IB/ALK-6 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB505
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Human, Mouse
Applications
Validated:
Western Blot
Cited:
ELISA Development, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # 88614
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human BMPR-IB/ALK-6
Lys14-Arg126
Accession # O00238
Lys14-Arg126
Accession # O00238
Specificity
Detects human and mouse BMPR-IB/ALK-6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant mouse (rm) BMPR‑IB and no cross‑reactivity with recombinant human (rh) BMPR‑IA, rmBMPR‑IA, or rhBMPR‑II is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for Human/Mouse BMPR-IB/ALK-6 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human BMPR-IB/ALK-6 Fc Chimera (Catalog # 505-PR)
Sample: Recombinant Human BMPR-IB/ALK-6 Fc Chimera (Catalog # 505-PR)
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from ascites
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: BMPR-IB/ALK-6
BMPR-IB, also known as ALK-6, is a type I serine/threonine kinase receptor that associates with a type II TGF-beta receptor superfamily member to form a heteromeric signaling receptor complex. BMPR-IB is expressed during embryogenesis and in adult brain, bone, and hematopoietic stem cells.
Long Name
Bone Morphogenetic Protein Receptor IB
Alternate Names
ALK-6, BMPR1B, BMPRIB, CDw293
Gene Symbol
BMPR1B
UniProt
Additional BMPR-IB/ALK-6 Products
Product Documents for Human/Mouse BMPR-IB/ALK-6 Antibody
Product Specific Notices for Human/Mouse BMPR-IB/ALK-6 Antibody
For research use only
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