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Human/Mouse Olig3 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB24561

R&D Systems, part of Bio-Techne
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MAB24561-100
MAB24561-SP

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 257914

Product Specifications

Immunogen

E. coli-derived recombinant human Olig3
Met1-Lys272
Accession # Q7RTU3

Specificity

Detects human Olig3 in direct ELISAs. Detects mouse Olig3 in Immunohistochemistry. In direct ELISA, no cross-reactivity with recombinant human (rh) Olig1 or rhOlig2 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human/Mouse Olig3 Antibody

Olig3 antibody in 13 dpc Mouse Embryo Tissue by Immunohistochemistry (IHC-Fr).

Olig3 in 13 dpc Mouse Embryo Tissue.

Olig3 was detected in immersion fixed frozen sections of 13 dpc mouse embryo tissue using Mouse Anti-Human/Mouse Olig3 Monoclonal Antibody (Catalog # MAB24561) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Applications for Human/Mouse Olig3 Antibody

Application
Recommended Usage

Immunohistochemistry

5-25 µg/mL
Sample: Immersion fixed frozen sections of 13 dpc mouse embryo tissue

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Olig3

Olig3 belongs to the Olig family of basic-helix-loop-helix (bHLH) transcription factors. It is transiently expressed in different types of embryonic central nervous system progenitors but is absent in later stages of development.

Long Name

Oligodendrocyte Lineage Transcription Factor 3

Alternate Names

BHLHB7

Entrez Gene IDs

167826 (Human); 94222 (Mouse)

Gene Symbol

OLIG3

UniProt

Additional Olig3 Products

Product Documents for Human/Mouse Olig3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human/Mouse Olig3 Antibody

For research use only

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