Human/Mouse/Rat CCK-AR Antibody
R&D Systems, part of Bio-Techne | Catalog # AF2680
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat
Cited:
Rat
Applications
Validated:
Immunohistochemistry, Western Blot
Cited:
Immunohistochemistry-Frozen
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Product Specifications
Immunogen
Rat CCK-A R synthetic peptide
Lys256-Glu267
Accession # P30551
Lys256-Glu267
Accession # P30551
Specificity
Detects human, mouse, and rat CCK-A R.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for Human/Mouse/Rat CCK-AR Antibody
CCK-A R in Rat Pancreas.
CCK-A R was detected in perfusion fixed frozen sections of rat pancreas using 5 µg/mL Human/Mouse/Rat CCK-A R Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2680) overnight at 4 °C. Tissue was stained (red) and counterstained (green). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.Applications for Human/Mouse/Rat CCK-AR Antibody
Application
Recommended Usage
Immunohistochemistry
5-15 µg/mL
Sample: Perfusion fixed frozen sections of mouse heart and kidney and rat pancreas
Sample: Perfusion fixed frozen sections of mouse heart and kidney and rat pancreas
Western Blot
0.1 µg/mL
Sample: Recombinant Human CCK-A R
Recombinant Mouse CCK-A R
Recombinant Rat CCK-A R
Sample: Recombinant Human CCK-A R
Recombinant Mouse CCK-A R
Recombinant Rat CCK-A R
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CCK-AR
The physiologic actions of the cholecystokinin (CCK) family of peptide hormones are mediated through two classes of G protein-coupled receptors, CCK-A R and CCK-B R. CCK-A R is a 428 amino acid protein with 7 putative transmembrane domains. This GPCR is involved in gallbladder contraction, insulin secretion, and has also been described in specific regions of the central nervous system. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction.
Long Name
Cholecystokinin Receptor, Type A
Alternate Names
CCK-A R, CCK1R, CCKAR
Gene Symbol
CCKAR
UniProt
Additional CCK-AR Products
Product Documents for Human/Mouse/Rat CCK-AR Antibody
Product Specific Notices for Human/Mouse/Rat CCK-AR Antibody
For research use only
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