Human/Mouse/Rat IMPA1/IMP1 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB98901
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Accession # P29218
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human/Mouse/Rat IMPA1/IMP1 Antibody
Detection of Human. Mouse, and Rat IMPA1/IMP1 by Western Blot.
Western blot shows lysates of Jurkat human acute T cell leukemia cell line, NIH-3T3 mouse embryonic fibroblast cell line, and C6 rat glioma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human/Mouse/Rat IMPA1/IMP1 Monoclonal Antibody (Catalog # MAB98901) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for IMPA1/IMP1 at approximately 30 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.Applications for Human/Mouse/Rat IMPA1/IMP1 Antibody
Western Blot
Sample: Jurkat human acute T cell leukemia cell line, NIH‑3T3 mouse embryonic fibroblast cell line, and C6 rat glioma cell line
Formulation, Preparation, and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IMPA1/IMP1
IMPA-1/inositol(myo)-1(or 4)-monophosphatase 1 is a ubiquitous enzyme with broad specificity, which is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. IMPA-1 dephosphorylates myo-inositol monophosphatate to modulate intracellular signal transduction. IMPA-1 forms homodimers, and is abundantly expressed in brain. The magnesium-dependent phosphatase activity is inhibited by lithium, thereby depressing myo-inositol production, which may explain the anti-depressive and anti-manic effects of lithium therapy in bipolar disorder.
Long Name
Alternate Names
Gene Symbol
UniProt
Additional IMPA1/IMP1 Products
Product Documents for Human/Mouse/Rat IMPA1/IMP1 Antibody
Product Specific Notices for Human/Mouse/Rat IMPA1/IMP1 Antibody
For research use only