Human/Mouse S100A6 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF4584
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
Biotin
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
E. coli-derived recombinant mouse S100A6
Met1-Lys89
Accession # P14069
Met1-Lys89
Accession # P14069
Specificity
Detects human and mouse S100A6 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human (rh) S100A1, rhS100A2, and recombinant mouse S100A4 is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Human/Mouse S100A6 Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human and mouse S100A6
Sample: Recombinant Human and mouse S100A6
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: S100A6
Mouse S100A6 (also prolactin receptor-associated protein and calcyclin) is a 10 kDa member of the S100 family of calcium-binding proteins. S100A6 is 89 amino acids (aa) in length and contains two calcium-binding EF-hand domains (aa 12‑47 and 48‑83). Intracellularly, S100A6 will both noncovalently homodimerize and heterodimerize with S100B plus SGT1. Extracellularly, it is secreted via a noncanonical pathway and binds to RAGE, inducing apoptosis. It is expressed by neurons, endothelium, fibroblasts and glandular epithelia. Mouse S100A6 is 99% and 96% aa identical to rat and human S100A6, respectively.
Long Name
S100 Calcium Binding Protein A6
Alternate Names
CACY, MLN 4, PRA
Gene Symbol
S100A6
UniProt
Additional S100A6 Products
Product Documents for Human/Mouse S100A6 Biotinylated Antibody
Product Specific Notices for Human/Mouse S100A6 Biotinylated Antibody
For research use only
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