Human/Mouse STAT4 Antibody
R&D Systems, part of Bio-Techne | Catalog # PAF-ST4
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Mouse
Applications
Validated:
Immunoprecipitation, Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse STAT4 synthetic peptide
aa 675-749
aa 675-749
Specificity
Detects human and mouse STAT4. No cross-reactivity with the other STATs has been detected by immunoprecipitation or by Western blotting.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human/Mouse STAT4 Antibody
Application
Recommended Usage
Immunoprecipitation
1 µg/106 cells
Sample: Human peripheral blood lymphocytes, see our available Western blot detection antibodies
Sample: Human peripheral blood lymphocytes, see our available Western blot detection antibodies
Western Blot
0.2 µg/mL
Sample: Human peripheral blood lymphocytes
Sample: Human peripheral blood lymphocytes
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Sterile PBS to a final concentration of 0.2 mg/mL.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: STAT4
Signal transduction and activator of transcription 4 (STAT4) is a member of the Jak/STAT signal transduction pathway. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo or heterodimerizes with other STAT proteins, which then translocate to the nucleus and activate transcription of specific genes. STAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation.
Long Name
Signal Transducer and Activator of Transcription 4
Alternate Names
signal transducer and activator of transcription 4, SLEB11
Gene Symbol
STAT4
Additional STAT4 Products
Product Documents for Human/Mouse STAT4 Antibody
Product Specific Notices for Human/Mouse STAT4 Antibody
For research use only
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