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Human NRG1 Isoform GGF2 Antibody

R&D Systems, part of Bio-Techne | Catalog # AF2015

R&D Systems, part of Bio-Techne
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AF2015
AF2015-SP

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

ELISA Development (Capture)

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

E. coli-derived recombinant human NRG1 Isoform GGF2
Gly51-Cys248
Accession # NP_039256

Specificity

Detects human NRG1 Isoform GGF2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human (rh) NRG‑1 alpha EGF domain, rhNRG1-beta 1 extracellular domain, rhNRG1-beta 1 EGF domain, rhSMDF, and recombinant mouse NRG3 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human NRG1 Isoform GGF2 Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human NRG1 Isoform GGF2
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Neuregulin-1 Isoform GGF2

By alternative splicing, the Neuregulin 1 gene ecodes at least 10 secreted or membrane-bound proteins, all of which contain an EGF-like domain. Neuregulin 1 isoforms bind and signal via the ErbB family of receptor tyrosine kinases. Isoform GGF2 contains a unique kringle-like domain, plus Ig and EGF-like domains that are also present in multiple Neuregulin 1 isoforms.

Alternate Names

GGF2, Neuregulin1 Isoform GGF2

Entrez Gene IDs

3084 (Human); 211323 (Mouse); 112400 (Rat)

Gene Symbol

NRG1

UniProt

Additional Neuregulin-1 Isoform GGF2 Products

Product Documents for Human NRG1 Isoform GGF2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human NRG1 Isoform GGF2 Antibody

For research use only

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