Human Plexin B1 Antibody

R&D Systems, part of Bio-Techne | Catalog # AF3749

R&D Systems, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
AF3749
AF3749-SP
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Western Blot

Cited:

Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

View all Plexin B1 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Plexin B1
Leu35-Val150
Accession # O43157

Specificity

Detects human Plexin B1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human Plexin B3 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Plexin B1 Antibody

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human prostate

Western Blot

0.1 µg/mL
Sample: Recombinant Human Plexin B1

Reviewed Applications

Read 1 review rated 4 using AF3749 in the following applications:

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Plexin B1

Plexin B1 is a type I transmembrane protein that belongs to the Plexin family of semaphorin receptors. It is derived from a single peptide that undergoes proteolytic processing in its extracellular domain to form the non-covalently-linked heterodimer of the extracellular alpha subunit and the transmembrane beta subunit. Human Plexin B1 extracellular alpha subunit shares homology with semaphorins, HGF receptor and MSP receptor and contains a sema domain and three IPT/TIG domains. It functions as a receptor for semaphorin 4D/CD100. Multiple splice isoforms of Plexin B1 have been reported. Within the region used as immunogen, human Plexin B1 shares 90% and 97% amino acid sequence homology with mouse and canine Plexin B1, respectively.

Alternate Names

PLXN5, PLXNB1, Transmembrane Protein SEP

Entrez Gene IDs

5364 (Human); 235611 (Mouse); 316009 (Rat)

Gene Symbol

PLXNB1

UniProt

O43157

Additional Plexin B1 Products

Product Documents for Human Plexin B1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Plexin B1 Antibody

For research use only

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.