Human S1P3/EDG-3 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB7524A

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 776808

View all S1P3/EDG-3 Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human S1P3/EDG‑3
Accession # Q99500

Specificity

Detects human S1P3/EDG‑3 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human S1P3/EDG-3 APC-conjugated Antibody

Detection of S1P3/EDG-3 antibody in NS0 Mouse Cell Line Transfected with Human S1P3/EDG-3 and eGFP antibody by Flow Cytometry.

Detection of S1P3/EDG‑3 in NS0 Mouse Cell Line Transfected with Human S1P3/EDG-3 and eGFP by Flow Cytometry.

NS0 mouse myeloma cell line transfected with human S1P3/EDG-3 and eGFP was stained with either (A) Mouse Anti-Human S1P3/EDG-3 APC-conjugated Monoclonal Antibody (Catalog # FAB7524A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.

Applications for Human S1P3/EDG-3 APC-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: NS0 mouse myeloma cell line transfected with human S1P3/EDG-3 and eGFP
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: S1P3/EDG-3

Sphingosine 1-Phosphate receptor-3 (S1P3), also known as EDG-3, is a 378 amino acid (aa) seven-transmembrane receptor for the lysolipid phosphoric acid mediator, sphingosine 1-phosphate (S1P). S1P3 interactions with S1P induce a range of responses including vasoconstriction, brachycardia, vascular endothelial and smooth muscle cell proliferation and migration, heart and liver fibrosis, and coagulation-induced inflammation. Extracellular portions of human S1P3 show 74% aa identity with mouse and rat S1P3.

Long Name

Endothelial Differentiation Gene 3

Alternate Names

EDG3, LPB3, S1PR3

Entrez Gene IDs

1903 (Human); 13610 (Mouse); 306792 (Rat)

Gene Symbol

S1PR3

UniProt

Q99500 (Human)

Additional S1P3/EDG-3 Products

Product Documents for Human S1P3/EDG-3 APC-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human S1P3/EDG-3 APC-conjugated Antibody

For research use only

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