Human SLITRK6 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB7317
Key Product Details
Species Reactivity
Human
Applications
Immunocytochemistry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # 753826
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human SLITRK-6
Ile16-Ala604
Accession # Q9H5Y7
Ile16-Ala604
Accession # Q9H5Y7
Specificity
Detects human SLITRK-6 in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human SLITRK6 Antibody
SLITRK6 in Raji Human Cell Line.
SLITRK6 was detected in immersion fixed Raji human Burkitt's lymphoma cell line using Mouse Anti-Human SLITRK6 Monoclonal Antibody (Catalog # MAB7317) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to plasma membrane. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.Applications for Human SLITRK6 Antibody
Application
Recommended Usage
Immunocytochemistry
10 µg/mL
Sample: Immersion fixed Raji human Burkitt's lymphoma cell line
Sample: Immersion fixed Raji human Burkitt's lymphoma cell line
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SLITRK6
SLITRK6 (Slit and NTRK-like 6) is a 95 kDa (predicted) member of the SLITRK family of proteins. It is widely expressed in the embryo, including cells in limb bud mesenchyme, visceral organ primodia, cells of the dorsal thalamus, and cochlear plus vestibular sensory epithelium. In the ear, SLITRK6 is suggested to induce neurotrophin expression from cells, thus promoting sensory neuron survival and axon pathfinding. Mature human SLITRK6 is an 826 amino acid (aa) type I transmembrane protein. It contains a 593 aa extracellular domain (ECD) (aa 16-608) plus a 212 aa cytoplasmic region. The ECD possesses two LRR clusters, one that involves seven LRRs (aa 27-269), and a second that involves eight LRRs (aa 320-568). Over aa 16-604, human SLITRK6 shares 89% aa sequence identity with mouse SLITRK6.
Long Name
SLIT and NTRK-like Family, Member 6
Alternate Names
FLJ22774, MGC119595, MGC119596, MGC119597,4832410J21Rik, SLIT and NTRK-like family, member 6, SLIT and NTRK-like protein 6, slit and trk like gene 6
Gene Symbol
SLITRK6
UniProt
Additional SLITRK6 Products
Product Documents for Human SLITRK6 Antibody
Product Specific Notices for Human SLITRK6 Antibody
For research use only
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