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Human TL1A/TNFSF15 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB7441

R&D Systems, part of Bio-Techne
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MAB7441
MAB7441-SP

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse

Applications

Validated:

Neutralization, Western Blot

Cited:

Neutralization

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG1 Clone # 293327

Product Specifications

Immunogen

E. coli-derived recombinant mouse TL1A/TNFSF15
Ile94-Leu270
Accession # NP_796345.3

Specificity

Detects recombinant human TL1A in Western Blot and Neutralization

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Applications for Human TL1A/TNFSF15 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human TL1A/TNFSF15 (Catalog # 1319-TL)

Neutralization

Reichwald, K. et al. (2014) PLoS ONE. 9:e85793.
Reichwald, K. et al. (2014) PLoS ONE. 9:e105627.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 2 reviews rated 3.5 using MAB7441 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TL1A/TNFSF15

TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNFSF15. It is expressed predominantly in endothelial cells, and its expression is inducible by TNF-alpha and IL-1 alpha. TL1A binds with high affinity to DR3/TNFRSF25 on activated T cells.

Long Name

TNF-like 1

Alternate Names

TNFSF15, VEGI

Entrez Gene IDs

9966 (Human); 326623 (Mouse)

Gene Symbol

TNFSF15

UniProt

Additional TL1A/TNFSF15 Products

Product Documents for Human TL1A/TNFSF15 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human TL1A/TNFSF15 Antibody

For research use only

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