IFITM3/Fragilis Antibody (SR3629)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27788

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27788-100ul
NBP3-27788-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR3629

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IFITM3/Fragilis Antibodies »

Product Summary for IFITM3/Fragilis Antibody (SR3629)

Immunogen

A synthesized peptide derived from human IFITM3/Fragilis (Uniprot #: Q01628)

Specificity

Detects endogenous levels of total IFITM3/Fragilis

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IFITM3/Fragilis Antibody (SR3629)

Western Blot: IFITM3/Fragilis Antibody (SR3629) [NBP3-27788] -

Western Blot: IFITM3/Fragilis Antibody (SR3629) [NBP3-27788] - Western blot analysis of IFITM3/Fragilis expression in HeLa cell lysate.

Applications for IFITM3/Fragilis Antibody (SR3629)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IFITM3/Fragilis

Mouse IFITM3/CD225 (also Fragilis) is a 137 amino acids (aa) 2-transmembrane protein that belongs to the Fragilis family of interferon-inducible genes. It contains two terminal extracellular domains (aas 1 - 57 and 131 - 137) and one cytoplasmic region that potentially allows for multiple phosphorylations. The N-terminal extracellular region of mouse IFITM3 is 54%, 91% and 58% aa identical to the equivalent region in bovine, rat and human IFITM3, respectively. IFITM3 is believed to be involved in primordial germ cell clustering and regionalization.

Long Name

Interferon-induced Transmembrane Protein 3

Alternate Names

Fragilis, IP15, mil-1

Gene Symbol

IFITM3

Additional IFITM3/Fragilis Products

Product Documents for IFITM3/Fragilis Antibody (SR3629)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IFITM3/Fragilis Antibody (SR3629)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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