IgE Antibody (1E7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11412

Novus Biologicals, part of Bio-Techne
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NBP3-11412-0.025mg
NBP3-11412-0.1mg
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Key Product Details

Species Reactivity

Validated:

Sheep

Cited:

Human

Predicted:

Goat (100%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Cited:

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 1E7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IgE Antibodies »

Product Specifications

Immunogen

Recombinant ovine IgE1-2 expressed in E.coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for IgE Antibody (1E7)

Application
Recommended Usage

ELISA

1:500 - 1:2000
Application Notes
Use in Western Blot reported in scientific literature (PMID:34209808).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

<0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IgE

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

Long Name

Immunoglobulin E

Alternate Names

IgE, immunoglobulin heavy constant epsilon

Gene Symbol

IGHE

Additional IgE Products

Product Documents for IgE Antibody (1E7)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for IgE Antibody (1E7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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