IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48241
![Immunohistochemistry-Paraffin: IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted [NBP2-48241]](https://resources.bio-techne.com/images/products/IgM-Heavy-Chain-Antibody-IM260-+-IM373-+-ICO-30-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48241-img0001.jpg "Immunohistochemistry-Paraffin: IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted [NBP2-48241]")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Kappa/IgG2b Kappa Clone # Cocktail
Format
IHC-Prediluted
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Heavy chain of human IgM
Localization
Cytoplasm, Cell Surface and Secreted
Specificity
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This monoclonal antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Marker
B-Cell Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 Kappa/IgG2b Kappa
Description
The prediluted antibody does not require any mixing, dilution, reconstitution, or titration; the antibody is ready-to-use and optimized for staining.
Scientific Data Images for IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted
Immunohistochemistry-Paraffin: IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted [NBP2-48241]
Immunohistochemistry-Paraffin: IgM Heavy Chain Antibody (IM260 + IM373 + ICO-30) - IHC-Prediluted [NBP2-48241] - Formalin-fixed, paraffin-embedded human Tonsil stained with IgM Mouse Monoclonal Antibody (Cocktail)Applications for IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Human Chromosome Location: 14q32.33 Mol. Weight of Antigen: 50-75 kDa Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) The 7mL size is a pre-diluted size and no additional dilutions are required before using this item for the intended application.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10 mM PBS with 0.05% BSA
Format
IHC-Prediluted
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: IgM Heavy Chain
Alternate Names
Constant region of heavy chain of IgM, Ig Mu Chain C Region BOT, Ig Mu Chain C Region GAL, Ig Mu Chain C Region OU, immunoglobulin heavy constant mu, Immunoglobulin mu chain
Gene Symbol
IGHM
Additional IgM Heavy Chain Products
Product Documents for IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted
Product Specific Notices for IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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