IKBKAP Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB600-214

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (92%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all IKBKAP Antibodies »

Product Specifications

Immunogen

C-terminus of the human IKAP protein (proprietary)

Reactivity Notes

Human. Other species have not been tested. Immunogen has a 92% identity to rat, and 84% identity with mouse.

Specificity

Reacts with the C terminus of IKAP.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IKBKAP Antibody - BSA Free

Western Blot: IKBKAP AntibodyBSA Free [NB600-214]

Western Blot: IKBKAP AntibodyBSA Free [NB600-214]

Western Blot: IKBKAP Antibody [NB600-214] - Analysis of IKBKAP in Interleukin-1-stimulated 293 cells using NB600-214 at 1:500 dilution

Applications for IKBKAP Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500 -1:1000
Application Notes
Western blot: Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for their specific application.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IKBKAP

The transcription factor NF-kappa B coordinates the activation of numerous genes in response to pathogens and pro-inflammatory cytokines, and is, therefore, vital in the development of acute and chronic inflammatory diseases. NF-kappa B is activated by cytokine-activated IKB kinases (IKKs); IKK-alpha and IKK-beta isozymes are found in large complexes. Theses large, interleukin-1-inducible IKK complexes have been found to contain a new protein, termed IKK-complex-associated protein (IKAP), which can bind NIK and IKKs and assemble them into an active kinase complex. IKAP is a scaffold protein and a regulator for 3 different kinases involved in pro-inflammatory cytokine signaling.

Alternate Names

DYS, elongator complex protein 1, ELP1DKFZp781H1425, FD, FLJ12497, IKAPdysautonomia (Riley-Day syndrome, hereditary sensory autonomic neuropathy typeIII), IkappaB kinase complex-associated protein, IKI3, IKK complex-associated protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinasecomplex-associated protein, p150, TOT1

Entrez Gene IDs

8518 (Human)

Gene Symbol

ELP1

Additional IKBKAP Products

Product Documents for IKBKAP Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for IKBKAP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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