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IKBKAP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16936

Novus Biologicals, part of Bio-Techne
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NBP2-16936

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rabbit (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human IKBKAP. The exact sequence is proprietary.

Reactivity Notes

Rat (85%).

Localization

Cytoplasm; Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

150 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IKBKAP Antibody

Western Blot: IKBKAP Antibody [NBP2-16936]

Western Blot: IKBKAP Antibody [NBP2-16936]

Western Blot: IKBKAP Antibody [NBP2-16936] - A. 30 ug GL261 whole cell lysate/extract B. 30 ug Raw264.7 whole cell lysate/extract 5% SDS-PAGE IKAP antibody [C1C2], Internal dilution: 1:500 The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: IKBKAP Antibody [NBP2-16936]

Immunocytochemistry/ Immunofluorescence: IKBKAP Antibody [NBP2-16936]

Immunocytochemistry/Immunofluorescence: IKBKAP Antibody [NBP2-16936] - HeLa cells were fixed in iced-cold MeOH for 5 min. Green: IKBKAP protein stained by IKBKAP antibody, Internal diluted at 1:500. Blue: Hoechst 33343 staining.
Western Blot: IKBKAP Antibody [NBP2-16936]

Western Blot: IKBKAP Antibody [NBP2-16936]

Western Blot: IKBKAP Antibody [NBP2-16936] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 5% SDS PAGE gel, diluted at 1:1000.

Applications for IKBKAP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IKBKAP

The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. [provided by RefSeq]

Alternate Names

DYS, elongator complex protein 1, ELP1DKFZp781H1425, FD, FLJ12497, IKAPdysautonomia (Riley-Day syndrome, hereditary sensory autonomic neuropathy typeIII), IkappaB kinase complex-associated protein, IKI3, IKK complex-associated protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinasecomplex-associated protein, p150, TOT1

Gene Symbol

ELP1

UniProt

Additional IKBKAP Products

Product Documents for IKBKAP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IKBKAP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.