IL-1 RII Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32681

Novus Biologicals, part of Bio-Techne
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NBP1-32681
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Rat

Predicted:

Rhesus Macaque (94%). Backed by our 100% Guarantee.

Applications

Validated:

Chromatin Immunoprecipitation (ChIP), Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL-1 RII Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human IL-1 RII. The exact sequence is proprietary.

Localization

Membrane, Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-1 RII Antibody

Western Blot: IL-1 RII Antibody [NBP1-32681]

Western Blot: IL-1 RII Antibody [NBP1-32681]

Western Blot: IL-1 RII Antibody [NBP1-32681] - Various tissue extracts (50 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with IL1 Receptor 2 antibody [N3C3] diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: IL-1 RII Antibody [NBP1-32681]

Immunocytochemistry/ Immunofluorescence: IL-1 RII Antibody [NBP1-32681]

Immunocytochemistry/Immunofluorescence: IL-1 RII Antibody [NBP1-32681] - Analysis of methanol-fixed A549, using antibody at 1:500 dilution.
Immunohistochemistry: IL-1 RII Antibody [NBP1-32681]

Immunohistochemistry: IL-1 RII Antibody [NBP1-32681]

Immunohistochemistry: IL-1 RII Antibody [NBP1-32681] - Representative photomicrographs of IL-1beta receptor immunofluorescence staining of the cingulum (Bregma - 1.0) on P4. Image collected and cropped by CiteAb from the following publication (https://bmcneurosci.biomedcentral.com/articles/10.1186/s12868-019-0529-1), licensed under a CC-BY license.
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Applications for IL-1 RII Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris-Glycine (pH7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IL-1 RII

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.

Long Name

Interleukin 1 Receptor II

Alternate Names

CD121b, IL-1 R beta, IL-1RII, IL1R2, IL1RII

Gene Symbol

IL1R2

Additional IL-1 RII Products

Product Documents for IL-1 RII Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-1 RII Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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