IL-1 RII Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86550

Novus Biologicals, part of Bio-Techne
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NBP1-86550
NBP1-86550-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL-1 RII Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-1 RII Antibody

Western Blot: IL-1 RII Antibody [NBP1-86550]

Western Blot: IL-1 RII Antibody [NBP1-86550]

Western Blot: IL-1 RII Antibody [NBP1-86550] - Analysis in control (vector only transfected HEK293T lysate) and IL1R2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: IL-1 RII Antibody [NBP1-86550]

Immunohistochemistry-Paraffin: IL-1 RII Antibody [NBP1-86550]

Immunohistochemistry-Paraffin: IL-1 RII Antibody [NBP1-86550] - Staining of human stomach shows moderate positivity in apical membrane in glandular cells.
Immunohistochemistry-Paraffin: IL-1 RII Antibody [NBP1-86550]

Immunohistochemistry-Paraffin: IL-1 RII Antibody [NBP1-86550]

Immunohistochemistry-Paraffin: IL-1 RII Antibody [NBP1-86550] - Staining of human smooth muscle shows strong positivity in smooth muscle cells.
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Applications for IL-1 RII Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-1 RII

The protein encoded by the IL1R2 gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. (provided by RefSeq)

Long Name

Interleukin 1 Receptor II

Alternate Names

CD121b, IL-1 R beta, IL-1RII, IL1R2, IL1RII

Gene Symbol

IL1R2

Additional IL-1 RII Products

Product Documents for IL-1 RII Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-1 RII Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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