IL-1ra/IL-1F3/IL1RN Antibody (005)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89195

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-89195-100ul
NBP2-89195-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 005

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-1ra/IL-1F3 Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the human IL-1ra/IL-1F3/IL1RN.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for IL-1ra/IL-1F3/IL1RN Antibody (005)

Immunohistochemistry-Paraffin: IL-1ra/IL-1F3/IL1RN Antibody (005) [NBP2-89195]

Immunohistochemistry-Paraffin: IL-1ra/IL-1F3/IL1RN Antibody (005) [NBP2-89195]

Immunohistochemistry-Paraffin: IL-1ra/IL-1F3/IL1RN Antibody (005) [NBP2-89195] - Staining of human IL1RA in human kidney with rabbit monoclonal antibody (1:100).
Immunohistochemistry-Paraffin: IL-1ra/IL-1F3/IL1RN Antibody (005) [NBP2-89195]

Immunohistochemistry-Paraffin: IL-1ra/IL-1F3/IL1RN Antibody (005) [NBP2-89195]

Immunohistochemistry-Paraffin: IL-1ra/IL-1F3/IL1RN Antibody (005) [NBP2-89195] - Staining of human IL1RA in human skin with rabbit monoclonal antibody (1:100).

Applications for IL-1ra/IL-1F3/IL1RN Antibody (005)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-1ra/IL-1F3

IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.

Long Name

Interleukin 1 Receptor Antagonist

Alternate Names

DIRA, ICIL-1ra, IL-1F3, IL-1ra3, IL-1RN, IL1ra, IL1RN, MVCD4

Gene Symbol

IL1RN

Additional IL-1ra/IL-1F3 Products

Product Documents for IL-1ra/IL-1F3/IL1RN Antibody (005)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-1ra/IL-1F3/IL1RN Antibody (005)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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