IL-23 Antibody (mirikizumab) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28749PE

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-28749PE
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Functional

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Recombinant Monoclonal Human IgG4 Clone # mirikizumab

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-23 Antibodies »

Product Summary for IL-23 Antibody (mirikizumab) [PE]

Immunogen

IL-23

Clonality

Monoclonal

Host

Human

Isotype

IgG4

Applications for IL-23 Antibody (mirikizumab) [PE]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-23

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

Long Name

Interleukin 23

Alternate Names

IL-23 p19/IL-12 p40, IL-23p19/IL-12p40, IL23, SGRF

Gene Symbol

IL23A

Additional IL-23 Products

Product Documents for IL-23 Antibody (mirikizumab) [PE]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-23 Antibody (mirikizumab) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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