IL-23A/IL-23 P19 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76697

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Tagged Protein Expression

Species Reactivity

Validated:

Human, Mouse

Predicted:

Equine (94%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all IL-23 Antibodies »

Product Summary for IL-23A/IL-23 P19 Antibody - BSA Free

Immunogen

Antibody was raised against a peptide corresponding to 17 amino acids near the amino terminus of human IL-23. The immunogen is located within amino acids 40 - 90 of IL-23. Amino Acid Squence: REEGDEETTNDVPHIQC

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Pig (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-23A/IL-23 P19 Antibody - BSA Free

Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-76697]

Western Blot: IL-23A/IL-23 P19 AntibodyBSA Free [NBP1-76697]

Western Blot: IL-23A/IL-23 P19 Antibody [NBP1-76697] - Western Blot Validation in Mouse Tissue Lysate. Loading: 15 ug of lysates per lane. Antibodies: IL-23A/IL-23 P19 NBP1-76697 (1 ug/mL), 1h incubation at RT in 5% NFDM/TBST. Secondary: Goat anti-rabbit IgG HRP conjugate at 1:10000 dilution.
Immunocytochemistry/ Immunofluorescence: IL-23A/IL-23 P19 Antibody - BSA Free [NBP1-76697]

Immunocytochemistry/ Immunofluorescence: IL-23A/IL-23 P19 Antibody - BSA Free [NBP1-76697]

Immunocytochemistry/Immunofluorescence: IL-23A/IL-23 P19 Antibody [NBP1-76697] - Mouse Pancreas cells with IL-23 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: IL-23A/IL-23 P19 Antibody - BSA Free [NBP1-76697]

Immunohistochemistry-Paraffin: IL-23A/IL-23 P19 Antibody - BSA Free [NBP1-76697]

Immunohistochemistry-Paraffin: IL-23A/IL-23 P19 Antibody [NBP1-76697] - Mouse pancreas tissue with IL23 P19 antibody at 2 ug/ml.
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Applications for IL-23A/IL-23 P19 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2 ug/ml

Immunohistochemistry-Paraffin

2 ug/ml

Western Blot

0.25-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: IL-23

Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.

Long Name

Interleukin 23

Alternate Names

IL-23 p19/IL-12 p40, IL-23p19/IL-12p40, IL23, SGRF

Entrez Gene IDs

51561 (Human); 83430 (Mouse)

Gene Symbol

IL23A

UniProt

Q9NPF7

Additional IL-23 Products

Product Documents for IL-23A/IL-23 P19 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-23A/IL-23 P19 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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