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Key Product Details

Species Reactivity

Validated:

Human, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 15N6C6

Concentration

1.0 mg/ml

Product Summary for IL-23R Antibody (15N6C6)

Immunogen

A synthetic peptide corresponding to amino acids 288-315 of hIL-23 receptor was used as immunogen for this antibody.

Reactivity Notes

Chimpanzee, Orangutan (100%), Mouse, Porcine, Canine, Rhesus monkey (89%), Rat, Equine, Bovine (84%)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for IL-23R Antibody (15N6C6)

Western Blot: IL-23R Antibody (15N6C6) [NBP2-27091]

Western Blot: IL-23R Antibody (15N6C6) [NBP2-27091]

Western Blot: IL-23 R Antibody (15N6C6) [NBP2-27091] - Analysis using IL-23 receptor antibody. Lysate from (A) human HCT116, (B) Jurkat and C) mouse NIH 3T3 cells probed with IL-23 receptor antibody at 1 ug/mL.
Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) [NBP2-27091]

Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) [NBP2-27091]

Immunohistochemistry-Paraffin: IL-23 R Antibody (15N6C6) [NBP2-27091] - Human Appendix FFPE tissue section stained with IL-23 R antibody. Image from verified customer review.
Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) [NBP2-27091]

Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) [NBP2-27091]

Immunohistochemistry-Paraffin: IL-23 R Antibody (15N6C6) [NBP2-27091] - Analysis of IL-23 receptor in human colon tissue using IL-23 receptor antibody at 5 ug/mL.

Applications for IL-23R Antibody (15N6C6)

Application
Recommended Usage

Western Blot

1 - 3 ug/mL
Application Notes
There are multiple isoforms of IL-23 receptor. Researchers are encouraged to use a tool like BLAST to determine the suitability of this antibody for their testing.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 4 using NBP2-27091 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-23R

IL-23 is a heterodimeric cytokine that shares biological properties with proinflammatory cytokines. IL-23 is composed of the IL-12p40 soluble receptor subunit and a novel cytokine-like subunit related to IL-12p35, termed p19. IL-23 mediates it cellular function by binding to IL-23 receptor, which pairs with IL-12Rb1 to confer IL-23 responsiveness. However, hIL-12 does not bind to hIL-23 receptor. IL-23 has been shown to possess biological activities on T cells that are similar as well distinct from those of IL-12.

Long Name

Interleukin 23 Receptor

Alternate Names

IL-23 R, IL23R

Gene Symbol

IL23R

UniProt

Additional IL-23R Products

Product Documents for IL-23R Antibody (15N6C6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-23R Antibody (15N6C6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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