Key Product Details

Species Reactivity

Validated:

Human, Primate

Predicted:

Chimpanzee (100%), Orangutan (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 15N6C6

Format

Azide Free

Concentration

1.0 mg/ml

View all IL-23R Antibodies »

Product Summary for IL-23R Antibody (15N6C6) - Azide Free

Immunogen

A synthetic peptide corresponding to amino acids 288-315 of hIL-23 receptor was used as immunogen for this antibody.

Reactivity Notes

The amino acid sequence used as immunogen for this antibody is 89% in Mouse, Porcine, Canine and Rhesus Macaque, and 84% homologous in Rat, Equine and Bovine.

Specificity

There are multiple isoforms of IL-23 receptor. Researchers are encouraged to use a tool like BLAST to determine the suitability of this antibody for their testing.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for IL-23R Antibody (15N6C6) - Azide Free

Western Blot: IL-23R Antibody (15N6C6)Azide Free [NBP2-27092]

Western Blot: IL-23R Antibody (15N6C6)Azide Free [NBP2-27092]

Western Blot: IL-23R Antibody (15N6C6) - Azide Free [NBP2-27092] - Lysate from (A) human HCT116, (B) Jurkat and C) mouse NIH 3T3 cells probed with IL-23 receptor antibody at 1 ug/ml.
Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) - Azide Free [NBP2-27092]

Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) - Azide Free [NBP2-27092]

Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) - Azide Free [NBP2-27092] - Human Appendix FFPE tissue section stained with IL-23 R antibody. Image from verified customer review. Image using the standard format of this product.
Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) - Azide Free [NBP2-27092]

Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) - Azide Free [NBP2-27092]

Immunohistochemistry-Paraffin: IL-23R Antibody (15N6C6) - Azide Free [NBP2-27092] - Analysis of IL-23 receptor in human colon tissue using IL-23 receptor antibody at 5 ug/ml.

Applications for IL-23R Antibody (15N6C6) - Azide Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5ug/ml

Western Blot

1-3ug/ml~
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 ml sterile PBS

Format

Azide Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-23R

IL-23 is a heterodimeric cytokine that shares biological properties with proinflammatory cytokines. IL-23 is composed of the IL-12p40 soluble receptor subunit and a novel cytokine-like subunit related to IL-12p35, termed p19. IL-23 mediates it cellular function by binding to IL-23 receptor, which pairs with IL-12Rb1 to confer IL-23 responsiveness. However, hIL-12 does not bind to hIL-23 receptor. IL-23 has been shown to possess biological activities on T cells that are similar as well distinct from those of IL-12.

Long Name

Interleukin 23 Receptor

Alternate Names

IL-23 R, IL23R

Gene Symbol

IL23R

Additional IL-23R Products

Product Documents for IL-23R Antibody (15N6C6) - Azide Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-23R Antibody (15N6C6) - Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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