IL18R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85782

Novus Biologicals, part of Bio-Techne
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NBP1-85782
NBP1-85782-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL18R1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL18R1 Antibody

Immunocytochemistry/ Immunofluorescence: IL18R1 Antibody [NBP1-85782]

Immunocytochemistry/ Immunofluorescence: IL18R1 Antibody [NBP1-85782]

Immunocytochemistry/Immunofluorescence: IL18R1 Antibody [NBP1-85782] - Staining of human cell line U-2 OS shows localization to mitochondria. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: IL18R1 Antibody [NBP1-85782]

Immunohistochemistry-Paraffin: IL18R1 Antibody [NBP1-85782]

Immunohistochemistry-Paraffin: IL18R1 Antibody [NBP1-85782] - Staining of human lymph node shows moderate to strong membranous positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: IL18R1 Antibody [NBP1-85782]

Immunohistochemistry-Paraffin: IL18R1 Antibody [NBP1-85782]

Immunohistochemistry-Paraffin: IL18R1 Antibody [NBP1-85782] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
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Applications for IL18R1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL18R1

IL-18 receptor is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor alpha chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.

Alternate Names

CD218 antigen-like family member A, CD218a, CD218a antigen, CDw218a, cytokine receptor, IL-18R1, IL-18R-1, IL1R-rp, IL1RRPIL1 receptor-related protein, IL-1RrpIL18RA, interleukin 18 receptor 1, interleukin-18 receptor 1

Gene Symbol

IL18R1

Additional IL18R1 Products

Product Documents for IL18R1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL18R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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