ILT5/CD85a/LILRB3 Antibody (4F9)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-64329

Novus Biologicals, part of Bio-Techne
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NB100-64329
NB100-64329-0.025mg
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 4F9

Concentration

1.0 mg/ml

View all LILRB3/CD85a/ILT5 Antibodies »

Product Specifications

Immunogen

Monocyte derived dendritic cells

Specificity

NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for ILT5/CD85a/LILRB3 Antibody (4F9)

ILT5/CD85a/LILRB3 Antibody (4F9) Flow Cytometry: ILT5/CD85a/LILRB3 Antibody (4F9) [NB100-64329] -

Flow Cytometry: ILT5/CD85a/LILRB3 Antibody (4F9) [NB100-64329] -

Flow Cytometry: ILT5/CD85a/LILRB3 Antibody (4F9) [NB100-64329] - Figure A. StarBright Blue 580 conjugated Mouse anti Human CD19 and Alexa Fluor 647 conjugated Mouse IgG1 isotype control. Figure B. StarBright Blue 580 conjugated Mouse anti Human CD1 and Alexa Fluor 647 conjugated Mouse anti Human CD85j. All experiments performed on red cell lysed human blood gated on single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.

Applications for ILT5/CD85a/LILRB3 Antibody (4F9)

Application
Recommended Usage

Flow Cytometry

1:50-1:200

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:100

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LILRB3/CD85a/ILT5

LILRB3 is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signaling modulators and inhibitors of cell activation. LILRB3 may act as receptor for class I MHC antigens.

Alternate Names

CD85a, ILT5, LIR3

Gene Symbol

LILRB3

UniProt

Q8NHL6

Additional LILRB3/CD85a/ILT5 Products

Product Documents for ILT5/CD85a/LILRB3 Antibody (4F9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ILT5/CD85a/LILRB3 Antibody (4F9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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