CD85g / ILT7, a member of leukocyte immunoglobulin-like receptor family expressed on plasmacytoid dendritic cells, but not on myeloid dendritic cells and other peripheral blood leukocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for ILT7/CD85g/LILRA4 Antibody (17G10.2) [Janelia Fluor® 635]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: LILRA4/CD85g/ILT7

ILT7 (immunoglobulin-like transcript 7) is a member of leukocyte immunoglobulin-like receptor (LIR or LILR) gene family, also known as CD85g and LILRA4. It contains four extracellular Ig domains. In association with Fc epsilonR1 gamma, ILT7 forms a receptor complex that transduces ITAM-mediated signals. ILT7 is specifically expressed on plasmacytoid dendritic cells (pDCs), but not on myeloid dendritic cells and other peripheral blood leukocytes. ILT7 negatively regulates the innate immune functions of human pDCs. Cross-linking 17G10.2 antibody is able to trigger ILT7 mediated signaling.

Long Name

Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 4

Alternate Names

CD85g, ILT7

Gene Symbol

LILRA4

Additional LILRA4/CD85g/ILT7 Products

Product Documents for ILT7/CD85g/LILRA4 Antibody (17G10.2) [Janelia Fluor® 635]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for ILT7/CD85g/LILRA4 Antibody (17G10.2) [Janelia Fluor® 635]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

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Flow Cytometry

ILT7/CD85g/LILRA4 Antibody (17G10.2) [Janelia Fluor® 635]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62226JF635

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all LILRA4/CD85g/ILT7 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for ILT7/CD85g/LILRA4 Antibody (17G10.2) [Janelia Fluor® 635]

Flow Cytometry

Functional

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: LILRA4/CD85g/ILT7

Long Name

Alternate Names

Gene Symbol

Additional LILRA4/CD85g/ILT7 Products

Product Documents for ILT7/CD85g/LILRA4 Antibody (17G10.2) [Janelia Fluor® 635]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for ILT7/CD85g/LILRA4 Antibody (17G10.2) [Janelia Fluor® 635]

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