IMP Dehydrogenase 2/IMPDH2 Antibody (SR3949)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27817

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27817-100ul
NBP3-27817-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR3949

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IMP Dehydrogenase 2/IMPDH2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human IMP Dehydrogenase 2/IMPDH2 (Uniprot #: P12268)

Specificity

Detects endogenous levels of total IMP Dehydrogenase 2/IMPDH2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IMP Dehydrogenase 2/IMPDH2 Antibody (SR3949)

Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody (SR3949) [NBP3-27817] -

Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody (SR3949) [NBP3-27817] - Western blot analysis of HeLa cell lysate.

Applications for IMP Dehydrogenase 2/IMPDH2 Antibody (SR3949)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IMP Dehydrogenase 2/IMPDH2

IMPDH2 encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Long Name

Inosine 5'-Monophosphate Dehydrogenase 2

Alternate Names

IMDH2, IMP Oxireductase 2, IMPD2, IMPDH2

Gene Symbol

IMPDH2

Additional IMP Dehydrogenase 2/IMPDH2 Products

Product Documents for IMP Dehydrogenase 2/IMPDH2 Antibody (SR3949)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IMP Dehydrogenase 2/IMPDH2 Antibody (SR3949)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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