IMPA2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86352

Novus Biologicals, part of Bio-Techne
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NBP1-86352
NBP1-86352-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IMPA2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: WEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IMPA2 Antibody

Western Blot: IMPA2 Antibody [NBP1-86352]

Western Blot: IMPA2 Antibody [NBP1-86352]

Western Blot: IMPA2 Antibody [NBP1-86352] - Analysis in control (vector only transfected HEK293T lysate) and IMPA2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: IMPA2 Antibody [NBP1-86352]

Immunocytochemistry/ Immunofluorescence: IMPA2 Antibody [NBP1-86352]

Immunocytochemistry/Immunofluorescence: IMPA2 Antibody [NBP1-86352] - Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & mitochondria.
Immunohistochemistry-Paraffin: IMPA2 Antibody [NBP1-86352]

Immunohistochemistry-Paraffin: IMPA2 Antibody [NBP1-86352]

Immunohistochemistry-Paraffin: IMPA2 Antibody [NBP1-86352] - Staining of human kidney shows moderate cytoplasmic positivity in renal tubules.

Applications for IMPA2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IMPA2

IMPA2, also known as Inositol monophosphatase 2, has a 288 amino acid isoform that is 31 kDa and a short 261 amino acid that is 29 kDa, catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling, can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates, and serves as possible pharmacological target for lithium Li+ action in brain. Studies are being performed on the relationship of this protein to bipolar disorder, mood disorder, seizures, schizophrenia, febrile seizures, bipolar affective disorder, neisseria meningitides, pneumonia, tuberculosis, neuronitis, schizophrenia and leukemia. The protein has been shown to interact with HERPUD1, TNFRSF1H, INPP1, ISYNA1, and PLCG1 in inositol phosphate metabolism, metabolic pathways and phosphatidylinositol signaling system pathways.

Alternate Names

EC 3.1.3.25, IMP 2, IMP.18P, IMPase 2, inosine monophosphatase 2, inositol monophosphatase 2, inositol monophosphatase 2 variant 1, inositol monophosphatase 2 variant 2, inositol(myo)-1(or 4)-monophosphatase 2, Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2

Gene Symbol

IMPA2

Additional IMPA2 Products

Product Documents for IMPA2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for IMPA2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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