IMPDH1 Antibody (3G6)

Novus Biologicals, part of Bio-Techne | Catalog # H00003614-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3G6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IMP Dehydrogenase 1/IMPDH1 Antibodies »

Product Specifications

Immunogen

IMPDH1 (NP_000874, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC

Specificity

IMPDH1 - IMP (inosine monophosphate) dehydrogenase 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for IMPDH1 Antibody (3G6)

Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01]

Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01]

Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01] - IMPDH1 monoclonal antibody (M01), clone 3G6. Western Blot analysis of IMPDH1 expression in HeLa [L013V1].
Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01]

Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01]

Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01] - IMPDH1 monoclonal antibody (M01), clone 3G6 Analysis of IMPDH1 expression in Hela S3 NE.
ELISA: IMPDH1 Antibody (3G6) [H00003614-M01]

ELISA: IMPDH1 Antibody (3G6) [H00003614-M01]

ELISA: IMPDH1 Antibody (3G6) [H00003614-M01] - Detection limit for recombinant GST tagged IMPDH1 is approximately 0.03ng/ml as a capture antibody.

Applications for IMPDH1 Antibody (3G6)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IMP Dehydrogenase 1/IMPDH1

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Inosine 5'-Monophosphate Dehydrogenase 1

Alternate Names

IMPD1, IMPDH1, LCA11, RP10

Entrez Gene IDs

3614 (Human)

Gene Symbol

IMPDH1

OMIM

146690 (Human)

UniProt

NP_000874 (Human)

Additional IMP Dehydrogenase 1/IMPDH1 Products

Product Documents for IMPDH1 Antibody (3G6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IMPDH1 Antibody (3G6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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