Inhibin alpha Antibody (SR1673)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22103

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22103-100ul
NBP3-22103-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1673

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Inhibin A Antibodies »

Product Summary for Inhibin alpha Antibody (SR1673)

Immunogen

A synthesized peptide derived from human Inhibin alpha (Uniprot #: P05111)

Specificity

Detects endogenous levels of total Inhibin alpha

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Inhibin alpha Antibody (SR1673)

Western Blot: Inhibin alpha Antibody (SR1673) [NBP3-22103] -

Western Blot: Inhibin alpha Antibody (SR1673) [NBP3-22103] - Western blot analysis using NBP3-22103 in Human testis lysate.

Applications for Inhibin alpha Antibody (SR1673)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Inhibin A

INHA(A-inhibin subunit precursor, inhibin alpha subunit ),also called inhibin(alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.

Alternate Names

INHA, Inhibin A

Gene Symbol

INHA

Additional Inhibin A Products

Product Documents for Inhibin alpha Antibody (SR1673)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Inhibin alpha Antibody (SR1673)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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