INPP5A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89361

Novus Biologicals, part of Bio-Techne
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NBP1-89361
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all INPP5A Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for INPP5A Antibody

Immunohistochemistry-Paraffin: INPP5A Antibody [NBP1-89361]

Immunohistochemistry-Paraffin: INPP5A Antibody [NBP1-89361]

Immunohistochemistry-Paraffin: INPP5A Antibody [NBP1-89361] - Analysis in human endometrium and tonsil tissues. Corresponding INPP5A RNA-seq data are presented for the same tissues.
Western Blot: INPP5A Antibody [NBP1-89361]

Western Blot: INPP5A Antibody [NBP1-89361]

Western Blot: INPP5A Antibody [NBP1-89361] - Analysis in control (vector only transfected HEK293T lysate) and INPP5A over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: INPP5A Antibody [NBP1-89361]

Immunohistochemistry-Paraffin: INPP5A Antibody [NBP1-89361]

Immunohistochemistry-Paraffin: INPP5A Antibody [NBP1-89361] - Staining of human tonsil shows moderate cytoplasmic positivity in germinal center cells, as well as very weak positivity in a subset of non-germinal center cells.
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Applications for INPP5A Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: INPP5A

INPP5A is a gene which codes for a protein that functions as a major isoenzyme that hydrolyzes the calcium-mobilizing second messenger Ins(1,4,5)P3 in a signal-terminating reaction and is comprised of 412 amino acids, with a mass of approximately 48 kDa. Studies are being conducted in several diseases and disorders relating to this gene including oculocerebrorenal syndrome, cutaneous T cell lymphoma, squamous cell carcinoma, Fanconi syndrome, schizophrenia, carcinoma, and olivopontocerebellar atrophy. INPP5A has also been shown to have interactions with PLEK, YWHAZ, GRB2, INPP1, and IPMK in pathways such as the inositol phosphate metabolism pathway.

Alternate Names

43 kDa inositol polyphosphate 5-phophatase, CTCL tumor antigen HD-CL-02,5PTASE, DKFZp434A1721, EC 3.1.3.56, inositol polyphosphate-5-phosphatase, 40kD, inositol polyphosphate-5-phosphatase, 40kDa, inositol trisphosphate-5-phosphatase, 40kD, InsP3 5-phosphatase, MGC116947,5PTase, MGC116949, type I inositol-14,5-trisphosphate 5-phophatase, type I inositol-14,5-trisphosphate 5-phosphatase

Gene Symbol

INPP5A

Additional INPP5A Products

Product Documents for INPP5A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for INPP5A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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