INSIG-1 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-84095
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit
Concentration
0.5 mg/ml
Product Specifications
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human INSIG-1. Peptide sequence: LAAHGAPDADPAPRGRSAAMSGPEPGSPYPNTWHHRLLQRSLVLFSVGVV The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Scientific Data Images for INSIG-1 Antibody
![Western Blot: INSIG-1 Antibody [NBP2-84095]](https://resources.bio-techne.com/images/products/INSIG-1-Antibody-Western-Blot-NBP2-84095-img0001.jpg "Western Blot: INSIG-1 Antibody [NBP2-84095]")
Western Blot: INSIG-1 Antibody [NBP2-84095]
Western Blot: INSIG-1 Antibody [NBP2-84095] - Host: Rabbit. Target Name: INSIG1. Sample Tissue: Stomach Tumor lysates. Antibody Dilution: 1ug/mlApplications for INSIG-1 Antibody
Application
Recommended Usage
Western Blot
1.0 ug/ml
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: INSIG-1
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alternate Names
CL6, CL-6, INSIG-1, INSIG-1 membrane protein, insulin induced gene 1, insulin-induced gene 1 protein, MGC1405
Gene Symbol
INSIG1
Additional INSIG-1 Products
Product Specific Notices for INSIG-1 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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