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Insulin R/CD220 Antibody (INSR/2277R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07513

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # INSR/2277R

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Recombinant fragment of extracellular domain of human Insulin Receptor alpha (exact sequence is proprietary) (Uniprot: P06213)

Localization

Cytoplasm

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

135 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08838)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for Insulin R/CD220 Antibody (INSR/2277R)

Immunohistochemistry-Paraffin: Insulin R/CD220 Antibody (INSR/2277R) [NBP3-07513]

Immunohistochemistry-Paraffin: Insulin R/CD220 Antibody (INSR/2277R) [NBP3-07513]

Immunohistochemistry-Paraffin: Insulin R/CD220 Antibody (INSR/2277R) [NBP3-07513] - Formalin-fixed, paraffin-embedded human Placenta stained with Insulin R/CD220 Rabbit Recombinant Monoclonal Antibody (INSR/2277R).

Applications for Insulin R/CD220 Antibody (INSR/2277R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Insulin R/CD220

Insulin receptor plays a major part in the regulation of glucose homeostasis, which when malfunctioning can result in diabetes and cancer. Encoded by the INSR gene, insulin receptor has two isoforms produced by alternative splicing, HIR-B and HIR-A.

Long Name

Insulin Receptor

Alternate Names

CD220, INSR, InsulinR

Gene Symbol

INSR

UniProt

Additional Insulin R/CD220 Products

Product Documents for Insulin R/CD220 Antibody (INSR/2277R)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Insulin R/CD220 Antibody (INSR/2277R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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