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Insulin R/CD220 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16970

Novus Biologicals, part of Bio-Techne
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NBP2-16970

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Insulin R/CD220 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Insulin R/CD220. The exact sequence is proprietary.

Localization

Membrane; Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

156 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Insulin R/CD220 Antibody

Immunohistochemistry-Paraffin: Insulin R/CD220 Antibody [NBP2-16970]

Immunohistochemistry-Paraffin: Insulin R/CD220 Antibody [NBP2-16970]

Immunohistochemistry-Paraffin: Insulin R/CD220 Antibody [NBP2-16970] - Analysis of paraffin-embedded human lung cancer, using Insulin Receptor antibody at 1:250 dilution.

Applications for Insulin R/CD220 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Insulin R/CD220

After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Insulin Receptor

Alternate Names

CD220, INSR, InsulinR

Gene Symbol

INSR

UniProt

Additional Insulin R/CD220 Products

Product Documents for Insulin R/CD220 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Insulin R/CD220 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.