Integrin alpha 2/CD49b Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38902

Novus Biologicals, part of Bio-Techne
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NBP2-38902
NBP2-38902-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 2/CD49b Antibodies »

Product Summary for Integrin alpha 2/CD49b Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Integrin alpha 2/CD49b Antibody

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902] - Staining of human rectum shows moderate to strong membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902] - Staining of human cervix, uterine shows moderate cytoplasmic positivity in basal squamous epithelial cells.
Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP2-38902] - Staining of human endometrium, rectum, skin and urinary bladder using Anti-ITGA2 antibody NBP2-38902 (A) shows similar protein distribution across tissues to independent antibody NBP2-38995 (B).
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Applications for Integrin alpha 2/CD49b Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Alternate Names

CD49b, ITGA2, VLA-2 alpha

Gene Symbol

ITGA2

UniProt

P17301

Additional Integrin alpha 2/CD49b Products

Product Documents for Integrin alpha 2/CD49b Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 2/CD49b Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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