Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

CoraFluor 1

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2530A

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 2b beta 3 Antibodies »

Product Specifications

Immunogen

Chinese Hamster Ovary cell line, CHO-derived heterodimer of Human Integrin alpha2b (Leu32-Arg993, Accession P08514) and Human Integrin beta3 (Gly27-Asp718, Accession P05106)

Specificity

Detects Human Integrin alpha2b beta3 heterodimer in direct ELISAs. In direct ELISAs, no cross-reactivity with recomabint human (rh) Integrin alpha2b, rhIntegrin alpha5, rhIntegrin alpha5 beta6, rhIntegrin alpha8 beta1, rhIntegrin beta1, rhIntegrin beta2, rhIntegrin beta3, rhIntegrin beta5, rhIntegrin beta7, and recombinant mouse Integrin alpha2b beta3.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Integrin alpha 2b beta 3 Antibody (2530A) [CoraFluor™ 1]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Integrin alpha 2b beta 3

Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.

Alternate Names

BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GT1;GTA;HPA3;Integrin alpha-IIb;ITGA2B;PPP1R93

Additional Integrin alpha 2b beta 3 Products

Product Documents for Integrin alpha 2b beta 3 Antibody (2530A) [CoraFluor™ 1]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Integrin alpha 2b beta 3 Antibody (2530A) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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