Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Monoclonal Human IgG4 Clone # Hu114

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 4 beta 1 Antibodies »

Product Specifications

Immunogen

Human Integrin alpha4 beta1

Specificity

Detects human Integrin alpha4 beta1 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Natalizumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG4

Applications for Integrin alpha 4 beta 1 Antibody (Hu114) [DyLight 350]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha 4 beta 1

Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.

Alternate Names

CD49d, IA4

Additional Integrin alpha 4 beta 1 Products

Product Documents for Integrin alpha 4 beta 1 Antibody (Hu114) [DyLight 350]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Integrin alpha 4 beta 1 Antibody (Hu114) [DyLight 350]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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