Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21189

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL11293

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 4 beta 7/LPAM-1 Antibodies »

Product Summary for Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293)

Immunogen

This antibody was developed against a Synthetic Peptide of P13612. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293)

Western Blot: Integrin alpha 4 beta 7/LPAM-1 Antibody [NBP3-21189] -

Western Blot: Integrin alpha 4 beta 7/LPAM-1 Antibody [NBP3-21189] -

Analysis in human cell line MOLT-4.

Applications for Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293)

Application
Recommended Usage

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents for Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Integrin alpha 4 beta 7/LPAM-1 Antibody (CL11293)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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