Integrin alpha 5/CD49e Antibody (SAM1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18529

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Primate

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # SAM1

Concentration

1 mg/ml

View all Integrin alpha 5/CD49e Antibodies »

Product Summary for Integrin alpha 5/CD49e Antibody (SAM1)

Immunogen

U937 cells

Epitope

The mouse monoclonal antibody SAM1 recognizes an extracellular epitope of Integrin alpha 5/CD49e.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Integrin alpha 5/CD49e Antibody (SAM1)

Flow Cytometry: Integrin alpha 5/CD49e Antibody (SAM1) [NBP3-18529]

Flow Cytometry: Integrin alpha 5/CD49e Antibody (SAM1) [NBP3-18529]

Flow Cytometry: Integrin alpha 5/CD49e Antibody (SAM1) [NBP3-18529] - Separation of human Integrin alpha 5/CD49e positive monocytes (red-filled) from human Integrin alpha 5/CD49e negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human Integrin alpha 5/CD49e (SAM1) purified antibody (concentration in sample 1.7 ug/ml, GAM APC).
Flow Cytometry: Integrin alpha 5/CD49e Antibody (SAM1) [NBP3-18529]

Flow Cytometry: Integrin alpha 5/CD49e Antibody (SAM1) [NBP3-18529]

Flow Cytometry: Integrin alpha 5/CD49e Antibody (SAM1) [NBP3-18529] - Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human Integrin alpha 5/CD49e (SAM1) purified antibody (concentration in sample 1.7 ug/ml, GAM APC).

Applications for Integrin alpha 5/CD49e Antibody (SAM1)

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.4

Preservative

0.9% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Integrin alpha 5/CD49e

CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kDa and 24 kDa, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.

Alternate Names

CD49e, ITGA5, VLA-5 alpha

Gene Symbol

ITGA5

Additional Integrin alpha 5/CD49e Products

Product Documents for Integrin alpha 5/CD49e Antibody (SAM1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin alpha 5/CD49e Antibody (SAM1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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