Integrin alpha 6/CD49f Antibody (CL6957)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76523

Novus Biologicals, part of Bio-Techne
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NBP2-76523
NBP2-76523-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL6957

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 6/CD49f Antibodies »

Product Summary for Integrin alpha 6/CD49f Antibody (CL6957)

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: APYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSS

Epitope

PSISIVGTLEAEKER

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88)% and Rat (86)%

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 6/CD49f Antibody (CL6957)

Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523]

Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523]

Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Analysis in human placenta and skeletal muscle tissues. Corresponding ITGA6 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523]

Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523]

Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Staining of human uterine cervix shows weak to moderate basement membrane positivity in squamous epithelium.
Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523]

Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523]

Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Staining of human placenta shows strong basement membrane positivity in trophoblastic cells.
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Applications for Integrin alpha 6/CD49f Antibody (CL6957)

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 6/CD49f

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Alternate Names

CD49f, ITGA6, Platelet gpl, VLA-6

Gene Symbol

ITGA6

Additional Integrin alpha 6/CD49f Products

Product Documents for Integrin alpha 6/CD49f Antibody (CL6957)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 6/CD49f Antibody (CL6957)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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