Integrin alpha 8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86519

Novus Biologicals, part of Bio-Techne
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NBP1-86519
NBP1-86519-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCA

Localization

Membrane; Single-pass type I membrane protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Integrin alpha 8 Antibody

Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519]

Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519]

Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519]

Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519]

Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519] - Staining of human kidney shows strong membranous positivity in cells in glomeruli, while cells in tubules are negative.
Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519]

Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519]

Immunohistochemistry-Paraffin: Integrin alpha 8 Antibody [NBP1-86519] - Staining of human lung shows weak to moderate membranous positivity in pneumocytes.
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Applications for Integrin alpha 8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 8

ITGA8 is a gene that codes for a protein that functions in the genesis of kidneys and other organs by facilitating the recruitment of mesenchymal cells into epithelial structures as well as working as a neuronal receptor for TNC to regulate neurite outgrowth, and is made up of 1063 amino acids, weighs approximately 117 kDa. Studies are being conducted on several diseases and disorders including keratopathy, carcinoma, kidney disease, laryngitis, Parkinson's disease, glomerulonephritis, Alzheimer's disease, melanoma, hepatitis, and neuronitis. ITGA8 has also been shown to have interactions with FN1, ITGB1, ITGA3, NPNT, and VNT in pathways such as the CDK5, Tec kinases signaling, integrin-mediated cell adhesion, signal transduction, and hypertrophic cardiomyopathy pathways.

Alternate Names

ITGA8

Entrez Gene IDs

8516 (Human)

Gene Symbol

ITGA8

UniProt

P53708

Additional Integrin alpha 8 Products

Product Documents for Integrin alpha 8 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Integrin alpha 8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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